Science & Power Behind Our Vagus Nerve Ear Stimulation Device “Xen”

Think of your nervous system as your body’s Wi-Fi. When stress hits, the signal weakens. Xen, a Vagus Nerve ear stimulation device, helps restore that connection with gentle, science-backed stimulation so you can relax, recharge, and think clearly.

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Reprogram Your Body with Neuroscience

Every Xen session trains your nervous system to recover faster. This isn’t magic; it’s the science of your body and brain finally syncing up.

  • Clinically validated for stress and better sleep

  • Invented by Dr Richard Cartledge, a top cardiovascular surgeon and inventor.19 

  • Enhances parasympathetic activity (your body’s “rest and digest” mode).18

  • Backed by leading institutions and real-life results.

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Backed by Research, Proven by Results

From the University of Maryland to the Air Force Research Laboratory, Xen’s underlying technology has been tested and validated in multiple research settings.

The Vagus Nerve: Your Built-In Reset Button

Your Vagus Nerve acts like a reset switch between “fight or flight” and “rest and restore.”¹⁸ When it’s stimulated, your body slows your heart rate, deepens breathing, and helps promote relaxation.

That’s why users describe Xen as “a 15-minute nervous system reset.” It’s small, affordable, HSA/FSA eligible and easy to integrate, But powerful enough to retrain how your body responds to stress.¹²

What is Vagus Nerve Stimulation (VNS)?

Let’s demystify the term “Vagus Nerve stimulation (VNS).” It’s not sci-fi; it’s neuroscience you can feel. VNS works by gently sending electrical signals directly through the Vagus Nerve, the command center for stress, mood, and rest.

When your Vagus Nerve gets that gentle nudge, it tells your brain: “We’re safe, you can relax.” Scientists call this balancing the autonomic nervous system.

Research shows that a Vagus Nerve ear stimulation device supports better sleep, emotional regulation, and focus. In short, it’s your biology’s best-kept secret, which is now available as a pocket-sized transcutaneous Vagus Nerve stimulation device.

Discover Xen Technology

Experience the power of vagus nerve stimulation with our innovative Xen device. Learn how it works and discover the proven benefits.

How Xen Naturally Activates the Vagus Nerve

Xen delivers gentle waveforms through your ear directly targeting the vagal pathway that controls calm, focus, and rest.12 It’s advanced science, made simple into one sleek, easy-to-use device

Clinical research shows this same waveform improved sleep, energy, and relaxation within just two weeks. It’s a compact, travel-friendly wearable Vagus Nerve stimulation device designed for everyday use.

Here’s what’s happening behind the scenes:

  • Electrical waveforms travel from the Xen unit through your earbuds, directly signalling your nervous system to unwind.
  • These precise pulses (30 Hz, 200 μs — the same parameters used in clinical research) are delivered through Xen’s patented earbuds, helping restore your body’s natural balance.
HOW IT WORKS

Proven Benefits of Xen – Vagus Nerve Ear Stimulation Device

Why the Ear VNS Device Holds the Key to Wellness

Here’s why Vagus Nerve ear-based stimulation devices are such a breakthrough: they give direct access to the Vagus Nerve’s auricular branch, the part that’s easiest to reach through the ear.

The best part? You don’t need to “try harder to relax.” With Xen, your body does the work; you just get to feel the results with regular use.
  • Xen is a clinically studied VNS device for depression, shown to lift mood and support long-term emotional balance. 13,14,15
  • Gently teaches your body how to activate the Vagus Nerve for anxiety, triggering calm safely and naturally.
  • Recognized among the best devices to help you sleep, it activates the Vagus Nerve, enhancing focus and clarity. 13, 14
  • This portable external VNS device helps improve sleep score by 100% and boost daily energyanytime, anywhere. 13, 14
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Scientific Research Supporting Vagus Nerve Ear Stimulation Device

Your Frequently Asked VNS Questions, Simplified & Answered

Everything you need to know about the science behind the tiny Vagus Nerve ear stimulation device “Xen”, making a big difference in sleep and stress.

Vagus Nerve stimulator devices

Yes, Vagus Nerve ear stimulation devices like Xen by Neuvana are designed to support relaxation, better sleep, and improved focus. Studies show 100% of users reported better sleep scores¹³ ¹⁴, and 80% of users reported feeling more balanced and less stressed after two weeks of daily use²¹.

Clinical trials also confirm improved vagal tone, heart rate variability, and reduced stress markers.¹¹ Consistent use strengthens results over time, supporting deeper rest, calmer moods, and greater resilience.

Clinical and field studies show that consistent use of Xen, Neuvana’s Vagus Nerve ear stimulation device, leads to measurable improvements in stress resilience, mood, and sleep quality.

In an observational study with former professional athletes using Xen, it was found:

  • 100% reported better sleep scores¹³ ¹⁴
  • improved mood and reported sharper focus¹³ ¹⁴
  • showed significant boosts in overall well-being after just two weeks of daily sessions¹³ ¹⁴.

Additional taVNS research using Xen’s parameters (30 Hz, 200 µs) demonstrated:

  • Improved vagal tone and heart rate variability¹¹
  • Better sleep latency and depth 
  • Increased energy levels after several weeks of use¹³ ¹⁴.

In short, while individual results vary, the majority of Xen users experience noticeable improvements within the first few weeks, and continued use strengthens those effects over time.

Patience (and consistency) are your friends here. VNS effects rarely show fully overnight.

Most users of VNS devices like Xen begin noticing benefits within 2–4 weeks, including calmer mood, better sleep, and sharper focus.

With consistent use of Xen, the Vagus Nerve ear stimulation device, measurable improvements in sleep, focus, and mood begin to emerge within a few short weeks¹³ ¹⁴.