How to Use Xen

Your Guide to Using the Best Vagus Nerve Stimulation Device

If stress had a “mute” button, the best Vagus Nerve stimulation device, Xen by Neuvana, would be it. This isn’t some complicated lab gadget, it’s one of the most advanced Vagus Nerve stimulation devices available today.

  • Backed by research: Developed and validated by Walter Reed, AFRL, ASU, DARPA, the University of Maryland, and MIIH.

  • Naturally effective: Gentle pulses stimulate the Vagus Nerve.

  • No pills, just science: Helps reset the nervous system using neuroscience.

  • Everyday ready: Lightweight, portable, and easy to use anywhere.

  • Smart wellness choice: HSA/FSA eligible, money-back guaranteed, trusted by thousands.

GET YOUR XEN TODAY

Start Restoring Your Nervous System in 3 Easy Steps

Restoring balance doesn’t have to mean overhauling your entire lifestyle. With just 15 minutes a day, five times a week, the best Vagus Nerve stimulation device helps retrain your nervous system to respond better to stress and unwind faster.13, 14 It’s like a quick daily reset for your mind and body and a simple example of how to activate the Vagus Nerve for anxiety at home or on the go.

Step 1: Connect

Plug in your Xen earbuds into the Xen device and open the Neuvana App on your phone. It takes seconds to get started. You’ll be ready to begin your session anytime, anywhere.

Step 2: Create Your Session

Choose a Quick Start Session — Sleep, Calm, or Focus — to relax, refocus, or recharge. Or design your own session for a custom experience.

Step 3: Customize Your Session

Adjust the duration and intensity until it feels perfectly tuned, then add music to enhance the experience.

START YOUR FIRST SESSION

Consistency Turns Science Into Results

Your nervous system learns through repetition; that’s where consistency pays off. Using Xen, the best Vagus Nerve stimulation device, for 15 minutes daily, five times a week, helps strengthen your body’s natural relaxation response, improving how you handle stress, focus, and sleep. Small habits, big physiological shifts.
100%
Retired athletes achieved better sleep scores using Xen’s gentle taVNS technology.13, 14
Significant Improvement
Mental clarity and emotional balance improved significantly across participants.²¹
80%
Reported feeling less stressed and more centered after routine use.²¹
Whether you’re looking for calming devices for anxiety or a proven VNS device for depression, Xen helps rewire your stress response using clinically tested parameters.15
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Modes Designed to Match Your Mood & Energy

Whether you're unwinding after work, powering through a project, or trying to breathe between toddler meltdowns, Xen is the best Vagus Nerve stimulation device with three modes that adapt to you.

Sensation Mode (Rhythmic Patterns)

The easiest way to experience how your transcutaneous Vagus Nerve stimulation device works is through Sensation Mode.

1) Pair Waveform F with ocean patterns for deeper sleep.
2) Try Waveform A with highs and lows to ease stress fast.
3) Experiment to find your perfect balance.

Pro Tip: Stimulating the Vagus Nerve helps balance your body and calm the fight-or-flight response.

Sync Mode (Add Your Music)

Take your experience with Xen to the next level with Sync Mode, where your music becomes part of your session.

1) Pair your waveform with music for an immersive flow.
2) Stream from any platform, including Spotify, Apple Music, Tidal, YouTube, and more.

Pro Tip: Sync Mode connects with any audio that plays sound.

Ambient Mode (Sync with Mic)

Experience your surroundings in a whole new way with Ambient Mode, turning your external VNS device into a tool that connects you to every beat and sound around you.

1) Ideal for music festivals, concerts, or live shows.
2) Amplifies surrounding sounds while providing gentle Vagus Nerve stimulation.
3) Keeps you centered and in sync with the world around you.

Pro Tip: Ambient Mode works best in louder environments.

How Waveforms & Sensations Tune Your Nervous System

Everyone’s nervous system speaks its own language, and the best Vagus Nerve stimulation device helps you tune in. Through the Neuvana App, you can customize Xen’s sessions by adjusting waveforms, sensations, and intensity until it fits your body’s unique rhythm.

Understanding Waveforms

Think of waveforms as gentle electrical frequencies that communicate directly with your Vagus Nerve, the control center for stress, mood, and rest. They’re the foundation of every wearable Vagus Nerve stimulation device, helping you find equilibrium from the inside out.
  • Daily 30 Hz sessions for 15 minutes improved vagal tone and sleep in just two weeks.12
  • Users reported sharper focus and felt in a better mood. 13, 14
  • 100% measurably slept better, with smoother, deeper REM cycles using Xen’s waveforms. 13, 14

Understanding Sensations

Sensations are ‌subtle physical signals, like a soft tingling or warmth, that tell you your Vagus Nerve is being activated. Some people feel them right away; others don’t, but both benefit equally.
  • Even without feeling a sensation, users showed measurable gains in heart rate variability and mood balance. 11
  • Studies found improved vagal tone and sleep quality after just two weeks of 30 Hz sessions. 12
  • Consistent use of Xen, the best Vagus Nerve stimulation device, helps reduce fight-or-flight responses and build lasting calm. 18

Your Xen Waveforms: Balance Your Mood, Stress & Sleep

Personalize your journey with the best Vagus Nerve stimulation device by pairing each waveform with your unique wellness goal, whether it’s stress relief, better sleep, calm, focus, or balance. Consistent use helps your body build lasting calm and resilience.
SAVE YOUR FAVORITES
  • Waveform D: Build resilience to daily stress. 8,9
  • Waveform A: Soothe tension and lift mood. 15
  • Best for evenings or post-stress resets.
  • Waveform F: Calms your system and preps you for sleep.
  • Supports deeper, longer rest cycles.
  • Pair with Ocean Wave in Sensation Mode for a calmer bedtime, your go-to Vagus Nerve sleep device for unwinding.

  • Waveform E: Promotes deep, centered calm.
  • Waveform B: Ideal for meditation or quiet mornings.
  • Waveform C: Boosts clarity and focus.13, 14
  • Perfect for work, study, or creative flow.
  • Waveform R1: Enhances mood, HRV, and lasting calm. 12
  • Backed by studies validating Xen’s clinical effects and supporting the Vagus Nerve and sleep connection. 12,13,14

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exclusive tips

USE YOUR SALINE

Included in your Xen Box Set, are 4 pink saline vials. Break one off from the pack and twist it open, then pour it into your saline sprayer (also in your Xen Box Set). Using saline can help enhance the conductivity of the vagus nerve stimulation. Spray your left earbud twice before each session.

FIND YOUR FIT

Using the right size earbud will get the good vibes going. The earbud needs to fit snug in your inner ear canal for the signal to be sent to your vagus nerve. When you find the size that fits best in your ear, make sure the white dot is aligned with the "L" on the left earbud before starting your session.

NO ONE LIKES EAR WAX

Not even your vagus nerve. Turns out, to stimulate it, we need you to clear the way. Use a damp cotton swab to clean out your ears before a session and you'll be good to go!

(SUPER PRO-TIP: wipe your ears and earbuds out after a session as well to clear out the saline and prevent crystallization)

KEEP IT CLEAN

Be sure to clean your headphones every 3-5 uses. To clean:Remove the rubber earbuds from the earpieces and cleanse using a mild soap and water. Allow them to fully dry before reassembling. Once dry, reattach the earbuds, ensuring that the Left earbud has a white dot that aligns with the 'L' on the left earbud.

(SUPER PRO-TIP: Once the rubber earbuds are removed, check the inner conductive metal rod on the left earpiece for signs of debris or saline buildup. Gently remove any debris with a dry cloth only. Note: do not wet this component with any liquid.)

Got Questions About Xen? We’ve Got Answers

Here’s everything you need to know about the best Vagus Nerve stimulation device that’s helping thousands sleep more deeply, stress less, and live more.

Questions About Xen?

Yes – research shows transcutaneous Vagus Nerve stimulation3 improves sleep, focus, and mood by enhancing parasympathetic activity. In Xen studies, 100% of users reported measurably improved sleep13, 14, and 80% of users stated they felt more balanced and less stressed with daily use.²¹

The newest innovation is Xen by Neuvana, a physician-designed, earbud-based system recognized as one of the best Vagus Nerve stimulation devices for natural stress relief, better sleep, and improved focus. 

Backed by institutions like Walter Reed and MIIH, it safely delivers electrical signals directly through the ear to rebalance the nervous system and stands out among all VNS devices on the market.